The trip from Isolatorweg to Centraal Station on Amsterdam Metro takes about 37 min, with 1 transfer.
Step by step
Metro 50 (Ringlijn)
Board at Isolatorweg on Metro 50 (Ringlijn) towards Gein, and get off at Zuid (9 stops).
Isolatorweg → Station Sloterdijk → De Vlugtlaan → Jan van Galenstraat → Postjesweg → Lelylaan → Heemstedestraat → Henk Sneevlietweg → Amstelveenseweg → Zuid
Metro 52 (Noord/Zuidlijn)
Board at Zuid on Metro 52 (Noord/Zuidlijn) towards Noord, and get off at Centraal Station (5 stops).
Zuid → Europaplein → De Pijp → Vijzelgracht → Rokin → Centraal Station
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